Nuclear Medicine & Radiation Therapy

Christopher A. Basciano

Publications

• Special Issue Article
  Computational Fluid Dynamics Modeling of 90Y Microspheres in Human Hepatic Tumors
  Author(s): Christopher A. Basciano, Clement Kleinstreuer and Andrew S. KennedyChristopher A. Basciano, Clement Kleinstreuer and Andrew S. Kennedy
  
  The number of patients afflicted with liver tumors continues to rise being a major concern of international healthcare. Yttrium-90 microsphere radioembolization can be an effective and safe treatment of unresectable primary and secondary liver tumors, and has the potential to be a forefront treatment option for tumor-afflicted patients. Computational fluid-particle dynamics is a powerful research tool that can be used to understand the underlying physics of Yttrium-90 microsphere transport and deposition, leading to improved clinical strategies and ultimately to a better treatment of tumor-afflicted patients. Two representative, patient-inspired three-dimensional geometries of the hepatic arterial system with assumed connections to liver tumors have been considered. Experimentallyvalidated computational fluid-particle dynamics modeling results have shown the significant influence of v.. Read More»
  DOI: 10.4172/2155-9619.1000112

  Abstract PDF