Molecular Biology: Open Access

Chuku LC

Publications

• Research Article
  Restoration of Liver Function Status in High Fat Diet Streptozotocin Induced NIDDM in Wistar Rats by Antioxidant Supplementation
  Author(s): Chinaka NC, Monago-Ighorodje CC, Chuku LC and Agbawo EOChinaka NC, Monago-Ighorodje CC, Chuku LC and Agbawo EO
  
  The study on liver function status of high fat diet and low dose streptozotocin (HFD-STZ) induced NIDDM in Wistar rats placed on antioxidant supplementation was monitored in vitro. Some antioxidant rich substances which include some minerals and vitamins, α-lipoic acid, cinnamon powder, curcumin (Meriva®), cordyceps, resveratrol, quercetin, D-ribose-L-cysteine were assembled together in appropriate (RDA (Recommended Dietary Allowance)) proportions into corn oil and stored 4oC for use. Liver and kidney function test were assayed using standard analytical grade reagents and kits as well as good equipment’s. Data analysis was done with SPSS version 20.0 and significant level was set at p ≤ 0.05. A total of five groups were created and used for this study. After induction of diabetes, the treatment lasted for a total of 12 weeks, with analysis carried out at the 4th,.. Read More»
  DOI: 10.4172/2168-9547.1000228

  Abstract PDF