Journal of Surgery

Cristina Iosif

Publications

• Case Report
  Bolnav cu Gist Gastric Gigant; Supraviețuire Nesperată Prezentare de Caz
  Author(s): Mircea Gheorghe, D Predescu, N Copca, Cristina Iosif, F Băcanu and S ConstantinoiuMircea Gheorghe, D Predescu, N Copca, Cristina Iosif, F Băcanu and S Constantinoiu
  
  Background: Gastrointestinal Stromal Tumors (GIST) are rare neoplasms, with sever prognosis in advanced cases. Until the discovery of Tyrosin Kinase Inhibitors (TKI), the life expectancy was very poor for patient with metastatic tumors, postoperative relapses or unresectable disease. Introduction of TKI therapy provided an unexpected survival rate, controlling the disease with very good tolerance. Method: We present a case report representative for GIST pathology. It is the first case of our GIST series of patients, operated in General and Esophageal Surgery Clinic of “St. Mary” Hospital Bucharest. A multidisciplinary approach and a complex, multimodal, surgical and oncological treatment was applied, with good response confirmed by the long-term follow-up. A 79 years old patient was diagnosed in 2004 (at the age of 70 years) with giant gastric GIST. He underwent a total ga.. Read More»
  

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