Journal of Clinical Case Reports

D K Mitra

Publications

• Case Report
  Improvement in Sperm DNA Quality Following Simple Life Style Intervention: A Study in Fathers of Children with Non-Familial Sporadic Heritable Retinoblastoma
  Author(s): Shiv Basant Kumar, Surabhi Gautam, Madhuri Tolahunase, Bhavna Chawla, Raj Kumar Yadav, Prabin Kumar, D K Mitra and Rima DadaShiv Basant Kumar, Surabhi Gautam, Madhuri Tolahunase, Bhavna Chawla, Raj Kumar Yadav, Prabin Kumar, D K Mitra and Rima Dada
  
  Introduction and objectives: Genomic integrity of gametes is important for birth of healthy offspring. As compared to ova the sperm is more susceptible to mutation due to limited DNA damage detection and repair mechanism. Life style habits adopted by father before conception may adversely affect genomic DNA integrity in male gametes. Oxidative stress damages sperm nuclear and mitochondrial DNA. Complementary and alternative medical therapies such as yoga/meditation are being increasingly used as adjuncts to modern medicine in treatment of several clinical conditions. Therefore, in this pilot study, we analyzed the effects of yoga and meditation on seminal oxidative stress and sperm DNA integrity in fathers of children with non-familial sporadic heritable retinoblastoma (Rb) after intervention (3 and 6 months). Methods: A tot.. Read More»
  DOI: 10.4172/2165-7920.1000509

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