Cardiovascular Diseases & Diagnosis

Daliborka Bursác

Publications

• Research Article
  Cardiotoxicity of First-Line Chemotherapy in Patients with Advanced Non-Small Cell Lung Cancer
  Author(s): Daliborka BursácDaliborka Bursác
  
  Background: The main goal of chemotherapy is to destroy tumor cells at the maximum with minimal damage to healthy tissue, which is sometimes difficult to achieve due to the non-selectivity of chemotherapeutics. Cardiotoxicity become important in the past several years, as significant progress has been made in both, early diagnosis and the use of increasingly advanced antitumor drugs. The aim of this study was to establish the frequency of cardiotoxicity in the patients treated with the first-line chemotherapy (gemcitabine and cisplatin vs paclitaxel and carboplatin). Methods: This prospective study included 240 non-small cell lung cancer patients at the clinical stages III and IV. Patients are divided into groups according to the type of chemotherapy (gemcitabine and cisplatin versus paclitaxel and carboplatin) and cardiovascular co-morbidit.. Read More»
  DOI: 10.4172/2329-9517.1000345

  Abstract PDF