Nuclear Medicine & Radiation Therapy

Daniel Scott S Hippe

Publications

• Research Article
  Tc-99m MAA Mapping Prior to Y-90 Liver Radioembolization; Factors that may affect Pulmonary Shunt Fraction
  Author(s): Fatemeh Behnia, Daniel Scott S Hippe, Mohammad Saad Bermo, Saeed Elojeimy and Hubert VesselleFatemeh Behnia, Daniel Scott S Hippe, Mohammad Saad Bermo, Saeed Elojeimy and Hubert Vesselle
  
  Purpose: To evaluate differences in shunt fraction and possible factors contributing to these differences in patients undergoing Tc-99m macroaggregated albumin (MAA) mapping prior to selective internal radiation therapy (SIRT) with Y-90 microspheres. Materials and methods: Retrospective analysis was performed on data from 130 patients with hepatocellular carcinoma (HCC) or liver metastases, who underwent Y-90 radioembolization over a 6-year period. All patients who received treatment had undergone Tc-99m MAA mapping. Overall 141 Tc-99m MAA injections and 199 Y-90 treatments were performed. Three patients did not qualify for Y-90 treatment following Tc-99m MAA mapping due to high pulmonary shunt fraction. We compared pulmonary shunt fraction between patients with HCC and those with metastatic liver disease and between patients who had mapping of the entire liver, versus selective mappi.. Read More»
  DOI: 10.4172/2155-9619.1000332

  Abstract PDF