Nehru Hospital, PGIMER,
Sector 12, Chandigarh
India
Research Article
Impact of Integrating Pet-Ct in Radiotherapy Planning of Non-small Cell Carcinoma Lung: Dosimetric and Radiobiological Comparison
Author(s): Deepak Koppaka, Rakesh Kapoor, Amit Bahl, Anshuma Bansal, BR Mittal and Navneet SinghDeepak Koppaka, Rakesh Kapoor, Amit Bahl, Anshuma Bansal, BR Mittal and Navneet Singh
The integration of PET and CT scans allows the simultaneous use of biologic and anatomic imaging data for better delineating tumor and sparing normal critical structures. The aim of this study is to assess the impact on target volume delineation using CT vs. PETCT based plans, and to determine radiobiological effect on tumor and normal tissue by comparing Tumor control probability (TCP) & normal tissue complication probability (NTCP) of CT & PET-CT based plans. 15 patients of inoperable NSCLC planned for radical radiotherapy, underwent a planning CT scan of the thorax. Target volumes were contoured. Later PETCT images with the auto contoured MTV (Metabolic target volume) images, were fused with the planning CT images. Margins were similarly given to PETMTV for the generation of PET CTV and PET PTV. 3 Dimensional conformal radiotherapy (3DCRT) plans were made on the planning CT.. Read More»
DOI:
10.4172/2329-6771.1000139
Journal of Integrative Oncology received 495 citations as per Google Scholar report