Journal of AIDS & Clinical Research

Defa Zhang

Publications

• Research Article
  Prevalence and Associated Factors of HIV and CMV Co-Infection in Tianjin, China
  Author(s): Bei Jiang, Rui Su, Defa Zhang, Liying Gao, Ping Ma and Wei LuBei Jiang, Rui Su, Defa Zhang, Liying Gao, Ping Ma and Wei Lu
  
  The prevalence and associated factors of human immunodeficiency virus (HIV) and cytomegalovirus (CMV) coinfection in patients starting antiretroviral therapy (ART) in Tianjin, China are under-studied. We measured CMV DNA in plasma specimens of 1347 HIV-infected patients. T-cell dynamics were measured by flow cytometry. A total of 1347 patients participated in this study. 1288 (95.6%) were male. The median age was 36. Both CMV positive and CMV negative groups were similar apart from the higher proportion of homosexual/bisexual HIV transmission in CMV negative group and the older age in CMV positive group. According to the duration of first-line ART, we did not observe a significant difference between CMV positive and CMV negative groups. CD4 counts and CD4 nadir counts are independent risk factors for the prevalence of CMV in HIV infected patients. We found a high prevalence of CMV (12.. Read More»
  DOI: 10.4172/2155-6113.1000767

  Abstract PDF