Pulmonary & Respiratory Medicine

Delphine Farneti

Publications

• Research Article
  Cisplatin Administration at Outpatient Clinics is Safe Compared to the In- Patient Usual Protocol: Findings from a Comparative Study
  Author(s): Sébastien Couraud, Marie Coudurier, Anne-Claire Toffart, Marie Destors, Emmanuel Villar, Mélodie Carbonnaux, Gaëlle Fossard, Delphine Farneti, Pierre-Jean Souquet and Denis Moro-SibilotSébastien Couraud, Marie Coudurier, Anne-Claire Toffart, Marie Destors, Emmanuel Villar, Mélodie Carbonnaux, Gaëlle Fossard, Delphine Farneti, Pierre-Jean Souquet and Denis Moro-Sibilot
  
  Introduction: Cisplatin is widely used in thoracic oncology. Its main limiting adverse effect is renal toxicity. A huge intravenous hydration is known to delivery administration of high-dose cisplatin at out-patient (OP) clinic using a shorter intravenous hydration protocol. However, the safety of this strategy has never been investigated yet. Here, we aimed to provide a comparative study of creatinine clearance levels changes in OP compared to the standard inpatient protocol (IP). Method: This is a retrospective study comparing two centers: one using the IP standard protocol and the other the OP. We used a general linear model for a confounder-adjusted assessment of the mean difference in creatinine clearance between the two groups. Results: 227 patients were included (172 in IP and 55 in OP). Pre-cisplatin basal clearance levels were comparable b.. Read More»
  DOI: 10.4172/2161-105X.1000262

  Abstract PDF