International Journal of Neurorehabilitation

Denes V Agoston

Publications

• Research Article
  Time-Dependent Changes in Serum Level of Protein Biomarkers after Focal Traumatic Brain Injury
  Author(s): Elham Rostami, Andrea Gyorgy, Johan Davidsson, John Walker, Daniel Wingo, Maria Angeria, Bo-Michael Bellander, Denes V Agoston and Mårten RislingElham Rostami, Andrea Gyorgy, Johan Davidsson, John Walker, Daniel Wingo, Maria Angeria, Bo-Michael Bellander, Denes V Agoston and Mårten Risling
  
  Serum biomarkers could indicate the pathological changes during the secondary injury process after traumatic brain injury (TBI). Furthermore, they could reflect specific pathological processes following different types of TBI. Here we analyzed time-dependent changes of select protein biomarkers in serum samples collected from a rodent model of penetrating type of injury (pen-TBI). The model is a controlled penetration of a 2 mm thick needle-shaped object, which is accelerated into the brain tissue with a bullet from an air gun. The results obtained in the current study were compared to previously reported results of levels of serum biomarker following a rotational acceleration injury that mimics mild TBI. A total of 24 animals were used, grouped in normal controls, sham-operated and injured animals. The rats were sacrificed at day 1, day 3 and day 14 post-injury and serum samples were.. Read More»
  DOI: 10.4172/2376-0281.1000168

  Abstract PDF