Molecular Biology: Open Access

Desalegne Menegesha

Publications

• Research Article
  Association of Angiotensin Converting Enzyme (ACE) Gene Polymorphisms and Risk of Diabetic 2 Among Patients Visiting Bahirdar Felegehiwot Referral Hospital North West, Ethiopia
  Author(s): Tadele Tamiru Berhane, Nega Berhane Tamiru, Wagaw Sendeku and Desalegne MenegeshaTadele Tamiru Berhane, Nega Berhane Tamiru, Wagaw Sendeku and Desalegne Menegesha
  
  Background: Type 2 diabetes (T2DM) affect large population. There are many genetic and non genetic factors associated for the occurrence of T2DM. Genes of the renin angiotensin system angiotensin converting enzyme insertion/deletion gene polymorphism has been associated with the risk of type 2 diabetes. The aim of the present study was to investigate the association of angiotensin converting enzyme gene polymorphism, risk of type 2 diabetes. Methods: A total of 222 subjects (111 T2DM and 111 healthy controls) were collected from Bahir Dar Felegehiwot Referral Hospital and Bahir Dar town, respectively by using non-probability purposive sampling techniques. Minidray fully automated analyzer was used for biochemical tests. The ACE I/D genotypes were identified by Polymerase chain reaction (PCR) using appropriate primers and PCR reaction conditions... Read More»
  DOI: 10.4172/2168-9547.1000207

  Abstract PDF