Nuclear Medicine & Radiation Therapy

Diandra N Ayala-Peacock

Publications

• Research Article
  11C-Choline PET-CT Detection of Osseous Metastases versus Bone Scan in Newly Diagnosed High Risk Prostate Cancer Patients-A Pilot Study
  Author(s): Nasarachi E Onyeuku, Diandra N Ayala-Peacock, Pradeep Garg and A. William BlackstockNasarachi E Onyeuku, Diandra N Ayala-Peacock, Pradeep Garg and A. William Blackstock
  
  Purpose: Identification of osseous metastatic prostate adenocarcinoma (PCa) is traditionally based on bone scan and computerized tomography (CT) imaging. Positron emission tomography (PET) has been investigated to improve detection of metastatic disease. Given the high number of false positive and false negative results with 18-fluorodeoxyglucose (18F-FDG) PET, novel tracers including 11C-Choline have been investigated for earlier identification metastatic disease. We present a prospective pilot study comparing 11C-Choline PET/CT against traditional bone scan in detecting osseous metastases in newly diagnosed high risk PCa. Methods: High-risk PCa patients underwent a standard initial workup: H&P, transrectal US-guided biopsy, PSA evaluation, CT scan, and bone scan. An experimental 11C-Choline PET/CT scan served to evaluate the extent of disease and predict for occult metastases. P.. Read More»
  DOI: 10.4172/2155-9619.S6-017

  Abstract PDF