Turkey
Research Article
In Patients Who Underwent Total Thyroidectomy Some Non-Steroidal Antiinflammatory Drugs Effects on Thyroid Replacement Therapy
Author(s): Süleyman Kargin, Didem Tastekin, Azamet Cezik, Murat Cakir, Kemal Kılıç, M Sinan Iyisoy and Tevfik KüçükkartallarSüleyman Kargin, Didem Tastekin, Azamet Cezik, Murat Cakir, Kemal Kılıç, M Sinan Iyisoy and Tevfik Küçükkartallar
Objective: Non-steroid anti-inflammatory drugs can change serum thyroid hormone concentrations by binding to serum proteins. If misunderstood, this situation can give way to inappropriate diagnoses and faulty treatment planning for thyroid diseases in clinical practice. The purpose of our study was to investigate the effects of ketoprofen, lornoxicam, and etofenamate, which are frequently used in clinical practice, on thyroid function tests.
Methodology: The study covered 28 rabbits divided into 4 groups. Groups were administered intramuscular injections daily for 10 days. Thyroid hormones concentrations were tested in the blood samples end of day 10.
Results: An increase in free thyroxin level in the lornoxicam group was recorded on.. Read More»
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