Medicinal Chemistry

Divya Prakash Maurya

Publications

• Research Article
  Synthesis, Antifungal and Toxicity Screening of Newer Isoniazid Derivatives
  Author(s): Sadaf Jamal Gilani, Kandasamy Nagarajan, Divya Prakash Maurya, Deepti Katiyar, Richa Goel and Suroor A KhanSadaf Jamal Gilani, Kandasamy Nagarajan, Divya Prakash Maurya, Deepti Katiyar, Richa Goel and Suroor A Khan
  
  A series of Isoninicotinic acid hydrazide (INH) incorporated derivatives of thiazolidin-4-one (2a-h, 3a-h), azetidin-2- one (4a-h) and 1,3,4-oxadiazole (5a-h) were synthesized in satisfactory yield and pharmacologically evaluated for their in vitro antifungal activity. All the synthesized compounds were in good agreement with elemental and spectral data. A majority of the tested compounds showed good to moderate antifungal activity against all tested pathogenic fungal strains. To evaluate the toxicity of the compounds on liver, estimation of enzymes was also carried out. .. Read More»
  DOI: 10.4172/2161-0444.1000174

  Abstract PDF