Cancer Science & Therapy

Dona Sinha

Publications

• Research Article
  Chronic Low Level Arsenic Exposure Inflicts Pulmonary and Systemic Inflammation
  Author(s): Dona Sinha, Bidisha Mukherjee, Banani Bindhani, Kaustav Dutta, Hirak Saha, Priyanka Prasad and Manas Ranjan RayDona Sinha, Bidisha Mukherjee, Banani Bindhani, Kaustav Dutta, Hirak Saha, Priyanka Prasad and Manas Ranjan Ray
  
  Objective: To examine whether chronic low level arsenic (As) exposure (11-50 μg/L) from drinking water elicits inflammation and oxidative stress. Methods: Never-smoking pre-menopausal women (n=267) from Nadia district, West Bengal, India, were enrolled into two groups (i) control (n=122, median age 39 yr) from villages with <10 μg/L of As in groudwater, and (ii) exposed (n=145, median age 38 yr) from the same district where the groundwater As was 11-50 μg/L. As in water was measured by atomic absorption spectrophtometry with vapour generation assembly. Sputum cytology and hematology were done by standard procedures. Enzyme-linked immunosorbent assays were used to measure tumor necrosis factor-alpha (TNF-α), interleukin-6, 8, 10, 12 (IL-6, IL-8, IL-10, IL-12) and C-reac.. Read More»
  DOI: 10.4172/1948-5956.1000250

  Abstract PDF