Journal of Cytology & Histology

Donglei Z

Publications

• Research Article
  Comparison Study of E-cadherin Expression in Primary Breast Cancer and its Corresponding Metastatic Lymph Node
  Author(s): Liesheng L, Lei Y, Zhenshun S, Lijun Z, Donglei Z and Zhen YLiesheng L, Lei Y, Zhenshun S, Lijun Z, Donglei Z and Zhen Y
  
  Introduction: E-cadherin is an intercellular adhesion molecule, whose loss of expression may facilitate the process of cancer invasion and metastasis. Although the expression of E-cadherin has been widely studied in primary breast cancers, little is known about its expression at the corresponding metastatic lymph node. Here we comparatively studied their E-cadherin expression patterns and related them to the pathological data of breast cancer patients. Methods: Only lymph nodes which were pathologically identified as metastases were included in this study to pair up the primary tumors. The quantitative real-time PCR (Q-RT-PCR) technique was used to assess the Ecadherin RNA expression levels in invasive ductal breast cancer subjects. E-cadherin gene copies were normalized using beta-actin gene copies. ER, PR, cerbB2 expressions in the primary t.. Read More»
  DOI: 10.4172/2157-7099.1000248

  Abstract PDF