Saudi Arabia
Review Article
Cytogenetics, Molecular Genetics and Epigenetics and Their Impact on The Management of Acute Lymphoblastic Leukemia
Author(s): Al-Anazi WK, Dridi W and Al-Anazi KAAl-Anazi WK, Dridi W and Al-Anazi KA
The recent improvements in the outcomes of patients with acute lymphoblastic leukemia reflect the progress in the field of diagnostics and the achievements in therapeutic interventions. In particular, the availability of more advanced technology in the cytogenetic and molecular laboratories has resulted in the stratification of patients into specific risk groups and thus several novel agents as well as targeted therapies have been introduced. Additionally, precision medicine will be applicable in the near future and thus the recent developments will facilitate the provision of safer modalities of therapy that may ultimately yield not only higher responses but also improved survival rates.
This review represents a recent update on the role of various cytogenetic assays and molecular techniques in patients with acute lymphoblastic leukemia. It is composed of a number of sectio.. Read More»
DOI:
10.4172/1747-0862.1000308
Molecular and Genetic Medicine received 3919 citations as per Google Scholar report