Division of Biomedical Statistics and Bioinformatics, Mayo Clinic, Rochester, MN, USA
Biography
Dueck AC, Division of Biomedical Statistics and Bioinformatics, In planning oncology phase II and phase III clinical trials, the size of the expected effect for endpoints such as tumor response and overall survival are key parameters driving the sample size. We applied the empirical rule effect size approach, also known as the ½ standard deviation (SD) method, to define clinically significant effect sizes for overall survival and tumor response endpoints in a series of clinical trials. Mayo Clinic, Rochester, MN, USA
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