India
Research Article
Zinc Improves the Bone Mechanical Strength in Ovariectomized Rat Model by Restoring Bone Composition and Hydroxyapatite Crystallite Dimension
Author(s): Payal Bhardwaj, Durg Vijay Rai and Mohan Lal GargPayal Bhardwaj, Durg Vijay Rai and Mohan Lal Garg
Purpose: Osteoporosis is a bone metabolic disorder which is well known to increase bone porosity and is the outcome of various factors like ageing, genetic, nutritional deficiency, decreased calcium uptake, and last but the most important hormonal imbalances. Hormonal imbalance is one of the major factors affecting women worldwide and leading to osteoporosis. Trace elements play a very essential role in number of pathological conditions. Ingestion of zinc in the early stages of bone loss may be more beneficial in mitigating bone loss and also in improving the overall strength of the bone. In the current work, we have intended to extract the information pertaining to the mechanical strength of bone, bone tissue composition and hydroxyapatite crystallite size upon supplementing zinc in the osteopenic condition. Methods: Forty eight wistar female rats in two set of twenty four animals ea.. Read More»
DOI:
10.4172/2376-1318.1000137
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