Canada
Review Article
Adherence to Antiretroviral Therapy for the Success of Emerging Interventions to Prevent HIV Transmission: A Wake up Call
Author(s): Jean B Nachega, Olalekan A Uthman, Edward J Mills and Thomas C QuinnJean B Nachega, Olalekan A Uthman, Edward J Mills and Thomas C Quinn
Despite recent successes in several HIV prevention trials, the epidemic continues to increase in many countries. The most successful biomedical interventions to prevent HIV have been the use of Antiretroviral Therapy (ART) to Prevent Mother-To-Child Transmission (PMTCT), and sexual transmission via microbicides, PreExposure Prophylaxis (PrEP), and treatment of the infected person within discordant couples. In addition medical male circumcision has also been shown to be highly effective in prevention of HIV acquisition. However, emerging data demonstrate that adherence to several of these prevention interventions is critical. ART adherence during and after pregnancy has been shown to be significantly below that recommended for adequate virologic suppression, particularly during the postpartum period. Five recent PrEP trials also demonstrate that the success of PrEP as a public health i.. Read More»
DOI:
10.4172/2155-6113.S4-007
Journal of AIDS & Clinical Research received 5264 citations as per Google Scholar report