Functional Foods and Nutraceuticals Laboratory (FFNL),
Postal code 21545 Alexandria
Egypt
Research Article
Effect of Lentil and Buffalo Whey Protein Hydrolysates on Histopathology of Liver and Kidney in Diabetic Rats
Author(s): Gehan Hassan Bisar, Mokhtar Youssef, Khaled El Saadany, Wedad Mohamed El-Kholy and Ehab KheadrGehan Hassan Bisar, Mokhtar Youssef, Khaled El Saadany, Wedad Mohamed El-Kholy and Ehab Kheadr
This study was undertaken to evaluate the effects of protein hydrolysate prepared from lentil and buffalo whey proteins on body weight and histopathology of alloxan induced diabetic rats. Seventy two male albino rats were randomly divided into non-diabetic, diabetic untreated and diabetic treated with lentil or buffalo whey protein hydrolysates with or without yogurt. Experimental diabetes was induced by a single intraperitoneal (i.p) administration of alloxan (120 mg/kg body weight). Histopathological analyses were conducted on the liver and kidney tissues after 28 day of experiment. While the body weight was significantly decreased in the diabetic control group, there were no significant difference in diabetic treated group (P<0.05). Destruction of the liver architecture of the hepatocytes in the diabetic group showed the signs of steatosis, fibrosis and inflammation in the centr.. Read More»
DOI:
10.4172/2157-7099.1000489
Journal of Cytology & Histology received 2476 citations as per Google Scholar report