Environmental & Analytical Toxicology

Eldesoki S Ibrahim

Publications

• Research Article
  Thiocyclam-Induced Reproductive Toxicity, Oxidative Stress and Genomic DNA Damage in Testicular Tissues of Rats: Protective Effects of Green Tea Extract
  Author(s): Amr A Abd Allah, Eman A Ibrahim, Eldesoki S Ibrahim, Naglaa F Mahmoud and Mostafa M AfifyAmr A Abd Allah, Eman A Ibrahim, Eldesoki S Ibrahim, Naglaa F Mahmoud and Mostafa M Afify
  
  Thiocyclam is a broad-spectrum nereistoxin analogue insecticide which widely used for agricultural applications. The aim of this study is to investigate the protective effects of green tea (as a principal source of antioxidants) on Thiocyclam-Induced Reproductive Toxicity, Oxidative Stress and Genotoxicity in adult Male Rats. Forty adult male rats were randomly assigned into four groups: control, Thiocyclam (ThC, 15.98 mg/kg b.w.), green tea extract (GTE, 2% w/v as the sole beverage) and (ThC+GTE) group. After 65 days of treatment, blood samples and testicular tissue were collected for measuring the oxidative stress parameters, testosterone level and DNA damage, whereas the reproductive organs were weighed, and Semen analysis and testicular histopathological studies was done. The results revealed that Thiocyclam administration induce a significant reduction in sperm count, sperm motil.. Read More»
  DOI: 10.4172/2161-0525.1000566

  Abstract PDF