Belarus
Research Article
HIV Drug Resistance at Patients on HAART and Transmitted HIV Drug Resistance (tHIVDR) in Treatment Naive Patients in Belarus
Author(s): Vladimir Eremin, Elena Gasich, Sviataslau Sasinovich, Oleg Suetnov and Igor KucherovVladimir Eremin, Elena Gasich, Sviataslau Sasinovich, Oleg Suetnov and Igor Kucherov
Of the 59 patients (adults) who have been identified to have a virus with a high level resistance to HAART drugs, in 38 (64.4%) patients mutation M184V/I was identified. In 27 (45.8%) patients (13 female and 14 male) K103N mutation was detected. In 20 (33.9%) patients (16 male and 4 female) we found G190G/S/A mutation. Of the 18 childrenpatients, born to HIV-infected mothers, in 15 (83.3%) cases (9 girls and 6 boys) we detected HIV resistance mutation M184V. In 10 (55.6%) and 2 (11.1%) cases mutations in position G190S and K103S were found, respectively. Of 82 samples collected from newly diagnosed HIV-infected antiretroviral naïve patients only 6 samples (7.3%) had other resistance mutations which can be classified as 'minor' or 'other' according to HIVDR database of Stanford University: L10V - PI minor mutation associated with resistance to most PIs when present with other muta.. Read More»
DOI:
10.4172/2155-6113.1000258
Journal of AIDS & Clinical Research received 5264 citations as per Google Scholar report