Transplantation Technologies & Research

Elena Zakharova

Publications

• Research Article
  The Prognostic Value of Late Kidney Transplant Rejection Pathology Characteristics
  Author(s): Ekaterina Stolyarevich, Ludmila Artyukhina, Elena Zakharova, Irina Kim, Ekaterina Ivanova and Natalia TomilinaEkaterina Stolyarevich, Ludmila Artyukhina, Elena Zakharova, Irina Kim, Ekaterina Ivanova and Natalia Tomilina
  
  Renal allograft rejection, represented by the wide spectrum of lesions with different pathogenesis, pathology patterns, clinical course and prognosis, still remains the most often cause of late graft dysfunction. Moreover, a combination of several factors, either of which may impact the post-transplant course, generally take place. We aimed to analyze the incidence of late renal allograft rejection variants, and to determine clinical factors and pathology features, influencing prognosis in the specific types of late renal allograft rejection. The data obtained from 361 patients with acute (n=227) or chronic (n=134) late allograft rejection (mean time after kidney transplantation 48.8 ± 46.1 months) were analyzed retrospectively. C4d expression was found in 34% cases of acute rejection and in 58% cases of chronic rejection (64% in chronic transplant glomerulopathy and 52% .. Read More»
  DOI: 10.4172/2161-0991.1000165

  Abstract PDF