Journal of AIDS & Clinical Research

Elizabeth J Mc Farland MD

Publications

• Research Article
  Intrahepatic Cholestasis of Pregnancy and Serum Bile Acids in HIV Infected Pregnant Women
  Author(s): Adriana Weinberg MD, Amanda Allshouse MS, Kay Kinzie NP, Alice Cho BS, Jill K Davies MD and Elizabeth J Mc Farland MDAdriana Weinberg MD, Amanda Allshouse MS, Kay Kinzie NP, Alice Cho BS, Jill K Davies MD and Elizabeth J Mc Farland MD
  
  Objectives: Intra-hepatic cholestasis of pregnancy (ICP) is uncommon, but has severe effects on pregnancy outcomes. ICP is characterized by elevated serum bile acids and liver enzymes and preferentially affects women with liver disorders. We compared bile acids and pregnancy outcomes of HIV-infected pregnant women, who commonly have elevated live enzymes, with uninfected controls. Methods: Twenty-four HIV-infected, including 2 co-infected with hepatitis C virus (HCV), and 25 uninfected women were tested during early and late pregnancy and postpartum. Results: After exclusion of the HCV-infected women, serum bile acids were similar in HIV-infected and uninfected participants. -glutamyl transpeptidase was elevated in HIV-infected compared with uninfected women during pregnancy and postpartum. Bilirubin and aspartate transaminase were higher in uninfe.. Read More»
  DOI: 10.4172/2155-6113.1000464

  Abstract PDF