Banha
Egypt
Research Article
New Possible Approach in Treatment of Experimental Induced Vaginal Atrophy by Bone Marrow-Derived Mesenchymal Stem Cells in Female Albino Rats (Histological Immunohistochemical and Biochemical Study)
Author(s): Eman Mohamed Faruk, Sherifa Abd El-Salam, Samia Mahmoud Manawy and Naglaa Yehia NafieEman Mohamed Faruk, Sherifa Abd El-Salam, Samia Mahmoud Manawy and Naglaa Yehia Nafie
Women after menopause have a lot of complains that negatively distress their life. In the modern years, a lot of conduction methods have been presented to relief undesirable symptoms. Bone marrow mesenchymal stem cells (BM-MSCs) can be recently used as a new therapeutic method treatment of many diseases and avoidance the hormonal therapy symptoms and complications sides effects that happened after menopause.
Aim: The aim of this research is to show a new approach in modification of the structure of vaginal mucosal atrophy by uses of (BM-MSCs) in induced ovariectomized rats.
Methods and results: Fifty female albino rats were used and divided randomly into five groups: control group, ovariectomized group, ovariectomized group plus estrogen (20 ug/kg/day for 4 weeks), ovariectomized with BMMSCs (107 MSCs/rat intravenously) and ovariectomi.. Read More»
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