Iraq
Research Article
Assessment Association between IFN- β2, AST and Natural Course of Infections with Hepatitis A and C Viruses
Author(s): Ali A Dawood, Mahmood AA Altobje and Eman Y ThanoonAli A Dawood, Mahmood AA Altobje and Eman Y Thanoon
Background: Hepatitis A and C viruses are common causing hepatitis (inflammation of liver). Acute and chronic liver infections are characterized by the expression of pro anti-inflammatory cytokines. Human interleukin 6 (IL-6) alliance is interferon beta 2 (designation used in this study) a multifunctional cytokine that interfere in the regulation, maturation and differentiation of immune response. Objective: The aim of this study is to demonstrate the level of IFN-β2 and correlates with AST level in patient’s serum with hepatitis A and C infections. Methods: We evaluate 46 patients presumably with acute HAV and chronic HCV whom have positive HAV IgM, HCV Ab respectively. AST chemical serum levels were detected using kit of an automated chemical Analyzer. IFN-β2 serum level was demonstrated using ELISA technique. Correlation between parameters was evaluated using SPSS a.. Read More»
Journal of Infectious Diseases and Medicine received 59 citations as per Google Scholar report