Japan
Review Article
Systematic Review: Effects of the Kampo Formula Yokukan-San-Ka-Chimpi-Hange on Behavioral and Psychological Symptoms of Dementia
Author(s): Masaki Baba, Shuji Yakubo, Eriko Fukuda, Yukiko Ueda, Tomohiro Hattori, Emiko Shiba, Masayoshi Soma, Yasutomo Arashima and Takao NamikiMasaki Baba, Shuji Yakubo, Eriko Fukuda, Yukiko Ueda, Tomohiro Hattori, Emiko Shiba, Masayoshi Soma, Yasutomo Arashima and Takao Namiki
Introduction: Randomized usual-case controlled studies on Japanese dementia patients with behavioral and psychological symptoms were conducted to examine the effects of Kampo medicine Yokukan-San (YKS) on the behavioral and psychological symptoms of dementia (BPSD). These studies showed that YKS is effective in treating BPSD. Yokukan-San-Ka-Chimpi-Hange is a Kampo medicine made by adding dried citrus peel and pinellia tuber to YKS. In Japan, we usually administer Yokukan-San-Ka-Chimpi-Hange as Kracie Yokukan-San-Ka-Chimpi-Hange extract granules (KB-83), produced by Kracie Pharma, Ltd. (Tokyo, Japan).
Methods: We investigated 3 trials carried out on the use of KB-83 for the treatment of severe dementia in elderly.
Results: KB-83 showed no change in core symptoms after administration in cases of dementia, but significant i.. Read More»
DOI:
10.4172/2327-5162.1000254
Alternative & Integrative Medicine received 476 citations as per Google Scholar report