Molecular Biology: Open Access

Emine Bayraktar

Publications

• Review Article
  OncoLncs: Long Non-Coding RNAs with Oncogenic Functions
  Author(s): Esra Bozgeyik, Emine Bayraktar, Arturo Chavez-Reyes and Cristian Rodriguez-AguayoEsra Bozgeyik, Emine Bayraktar, Arturo Chavez-Reyes and Cristian Rodriguez-Aguayo
  
  A decade before the discovery of non-coding transcripts, approximately 98% of the human genome was known as “transcriptional noise” or “junk DNA”. However, with the recent findings, non-coding transcripts are continuously turning into functional non-coding RNAs (ncRNA). NcRNAs comprise multiple classes of RNA transcripts that are not transcribed into proteins but have shown to regulate the transcription, stability, or translation of protein-coding genes in the mammalian genome. Nowadays the most studied ncRNAs are called miRNAs. They have been involved in the biogenesis and development of cancer. More recently, long non-coding RNAs (lncRNAs) were discovered and they have been shown not only to play a role in transcriptional and translational regulation, but also be involved in several diseases including cancer. LncRNAs are RNA transcripts longer than 200 nucleo.. Read More»
  DOI: 10.4172/2168-9547.1000162

  Abstract PDF