Khartoum
Sudan
Research Article
Molecular Detection of JCV in Urine and Blood Samples of Renal Transplant Patients in Khartoum State, Sudan
Author(s): Badri AM, Janay A, Jonas H, Liban AH, El Fadol ASM, El Hussein ARM, Elkhidir IM and Enan KABadri AM, Janay A, Jonas H, Liban AH, El Fadol ASM, El Hussein ARM, Elkhidir IM and Enan KA
Background: The present study aimed to investigate the infections of Polyomaviruses JCV (John Cunningham virus) in renal transplant recipients in Khartoum State in Sudan and to compare the results of the detection of JCV in urine and plasma.
Methodology: A total of 50 Plasma and 50 urine samples were collected randomly from renal transplant recipients attending Sudanese Renal Transplant society during period between January and February 2016. The samples were subjected to polymerase chain reaction (PCR) assay to detect the viral deoxyribonucleic acid (DNA).
Results: Among the 50 renal transplant patients the Polyomaviruses nucleic acid was detected in 24 plasma specimens (48%) and only in 14 urine specimens (28%) by using conventional PCR method.
Conclusion: JC Virus is related to clinical mani.. Read More»
DOI:
10.4172/2168-9547.1000178
Molecular Biology: Open Access received 607 citations as per Google Scholar report