Cancer Science & Therapy

Eric Dzintars

Publications

• Research Article
  Assessing the Dosimetric Consequence of Inter-fractional Setup Shifts on Helical TomoTherapy Plans with Independent Dose Calculation
  Author(s): Weihong He, Luis A Vazquez Q, Eric Dzintars and Nikos PapanikolaouWeihong He, Luis A Vazquez Q, Eric Dzintars and Nikos Papanikolaou
  
  This work studied on dosimetric impact due to inter-fractional uncertainties for one hundred patients from five different treatment sites (30 prostate, 26 head & neck, 18 lung, 17 pelvis, and 9 brain patients) for Tomotherapy modality. Daily setup shifts were quantified and grouped into systematic (mean daily setup shifts) and random shifts (fractionbased shifts with corresponding systematic shift subtraction). Both systematic and random shifts were incorporated into in-house independent point dose calculation software, MU-Tomo, to separately evaluate the systematic and random dosimetric variations. Systematic dosimetric variations showed large dose deviation, with the largest difference at -10.02% compared to the planned dose and 3% standard deviation. Mean random dosimetric variations showed relatively small dose deviation with the largest at -5.65% compared to the planned dose .. Read More»
  

  Abstract PDF