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Commentary
Immune System and Pituitary Tumors: TILs Death tears them Apart. A Review
Author(s): Emigdio José León-Toirac, Erick Robles Torres and Irma Vega GarcíaEmigdio José León-Toirac, Erick Robles Torres and Irma Vega García
Introduction: Pituitary tumors are common in general population, but the study of these tumors confronts some restrictions, including the inaccessibility of the gland for biopsy material. It has also been described that lymphocytic infiltration can be found adjacent to pituitary adenomas.
Objective: This article was conceived to collect some information to describe the involvement of immune system on pituitary tumors microenvironment and also to shed light to molecular mechanisms implicated on the pathogenesis of these diseases.
Methods: A search of the literature was done in Medline database between 1990 and 2014, using the search terms immune system and pituitary tumors. A review of 88 papers was performed including articles published mainly in English-language and with free access to full paper. The most recent refe.. Read More»
DOI:
10.4172/2157-7099.1000332
Journal of Cytology & Histology received 2334 citations as per Google Scholar report