Edmonton, AB
Canada
Review Article
Histopathology of the Human Brain in Neurocysticercosis
Author(s): Ericson DamettoEricson Dametto
Background: Neurocysticercosis (NCC) is a common parasitic disease of the Central Nervous System (CNS) caused by larval stages of Taenia solium (TS). It is an important cause of epilepsy, as well as sensory and motor deficits. NCC’s pathology relates to immunological and inflammatory interactions between host and parasite. Methods: In human brain, the larval stage of TS and surrounding nervous tissue were evaluated by immunohistochemistry using anti-CD3, anti-CD20, anti-CD68, Masson’s trichrome, and hematoxylin eosin. Photography registered histological details. Results: The microscopy of NCC’s lesions presents fibrosis, gliosis, perivascular infiltrate, edema, vascular changes, granulomatosis, and calcification. The cyst’s microscopy allows identifying capsule with microvilli and osmotic canalicull.. Read More»