Switzerland
Research Article
Caphosol® versus State-of-the-Art Mouth Care in Patients with Allogeneic Stem Cell Transplantation: A Randomized Controlled Trial
Author(s): Anja Kroner, Erik Aerts, Urs Schanz and Rebecca SpirigAnja Kroner, Erik Aerts, Urs Schanz and Rebecca Spirig
Objective: Oral mucositis (OM) is a common side effect of allogeneic stem cell transplantation and can lead to infections with increased morbidity, mortality, higher costs and an impact on the quality of patients’ lives. We conducted a study on the stem cell transplantation ward of a Swiss university hospital which treats oral mucositis with state-of-the-art measures.
Method and participants: In a randomized controlled, non-blinded trial involving 72 patients with allogeneic stem cell transplantation, we investigated the effectiveness of the oral rinse Caphosol® versus filtered water, in terms of duration of OM (primary endpoint), manifestation of OM and occurrence of pain, dry mouth, swallowing problems and changes in perception of taste (secondary endpoints).
Results: Results show Caphosol® had no eff.. Read More»
DOI:
10.4172/2167-1168.1000359
Journal of Nursing & Care received 4230 citations as per Google Scholar report