Pharmaceutical Regulatory Affairs: Open Access

Esmaeili D

Publications

• Review Article
  The Proteins of Type IV Secretion System as Promising Candidates for Helicobacter pylori Vaccine
  Author(s): Esmaeili D, Khaledi A and Bahador AEsmaeili D, Khaledi A and Bahador A
  
  Helicobacter pylori are component of class 1 carcinogens and there is a close association between the incidence of gastric cancer and high prevalence of infection with this bacterium. The risk of gastric cancer associated with H. pylori infection in industrialized and developing countries are estimated to be 80% and 70% respectively. CagA is the important virulence factor in this bacterium and all of the strains involved in gastric cancer are CagA positive. This factor is secreted into host cells by type IV secretion system. CagA and type IV secretion system in H. pylori encoded by the cag .. Read More»
  DOI: 10.4172/2167-7689.1000148

  Abstract PDF