Molecular Biomarkers & Diagnosis

Eugène HJM Jansen

Publications

• Research Article
  Long Term Stability of Parameters of Lipid Metabolism in Frozen Human Serum: Triglycerides, Free Fatty Acids, Total-, HDL- and LDL-cholesterol, Apolipoprotein-A1 and B
  Author(s): Eugène HJM Jansen, Piet K Beekhof and Erna SchenkEugène HJM Jansen, Piet K Beekhof and Erna Schenk
  
  Background: In large epidemiological studies it is important to test the stability of biomarkers as a function of both temperature and duration of storage. In this study the stability of seven lipid parameters have been tested in human serum samples after storage at three different temperatures up to 1 year. Methods: Serum samples of 16 human individuals were used in this study. The concentration of all parameters have been determined at T=0 and at several time points up to 1 year after storage at –20°C, –70°C and –196°C. Results: Most of the lipid biomarkers, cholesterol, triglycerides HDL- and LDL cholesterol, apolipoprotein-A1 and –B are stable on long-term storage for one year at the three temperatures tested. The levels of both HDL- and LDL cholesterol showed a small decreas.. Read More»
  DOI: 10.4172/2155-9929.1000182

  Abstract PDF