Molecular Biomarkers & Diagnosis

Eugène HJM Jansen

Publications

• Research Article
  The Effect of Smoking on Biomarkers of (Anti) oxidant Status
  Author(s): Eugène HJM Jansen, Piet Beekhof and Tatjana RuskovskaEugène HJM Jansen, Piet Beekhof and Tatjana Ruskovska
  
  The influence of smoking on the levels of several biomarkers of oxidative stress, antioxidant status and redox status have been investigated in 48 healthy men with a mean age of 25 y. The biomarkers of oxidative stress are the reactive oxygen metabolytes (ROM) and the total oxidant status (TOS). The biomarkers for the antioxidant activity are the biological antioxidant potential (BAP), the ferric reducing ability of plasma (FRAP), the total antioxidant status (TAS), the assay for the defense against the oxidation by hypochlorous acid (OXY) and uric acid (UA). The total thiol levels (TTL) have been measured as a biomarker for the redox status. The average concentration of ROM was 14% higher in smokers compared with non-smokers (p<0.05), whereas TOS was 4.9% higher (not statistically significant).The average concentrations of BAP, FRAP and TAS decreased with smoking with 3.6 (p<0... Read More»
  DOI: 10.4172/2155-9929.1000207

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