Cancer Science & Therapy

Fabiola Iagher

Publications

• Research Article
  Exercise and Shark Liver Oil Supplementation Reduce Tumor Growth and Cancer Cachexia in Walker 256 Tumor Bearing Rats
  Author(s): Marcelo Kryczyk, Jaisson Bordignon, Fabiola Iagher, Everson Araujo Nunes, Ricardo Key Yamazaki, Gleisson Alisson Perreira de Brito, Juliano Machado, Katya Naliwaiko, Aldre IP Tanhoffer, Ricardo A Tanhoffer and Luiz Cláudio FernandesMarcelo Kryczyk, Jaisson Bordignon, Fabiola Iagher, Everson Araujo Nunes, Ricardo Key Yamazaki, Gleisson Alisson Perreira de Brito, Juliano Machado, Katya Naliwaiko, Aldre IP Tanhoffer, Ricardo A Tanhoffer and Luiz Cláudio Fernandes
  
  This study investigated whether exercise associated to shark liver oil supplementation (1 g/kg b.w./day) affects tumor growth, cachexia, lipid peroxidation and proteins expression involved in cell death in Walker 256 tumorbearing rats. Animals were divided into 4 groups: sedentary tumor-bearing (W), sedentary tumor-bearing shark liver oil supplemented (WSL), exercised tumor-bearing (EW) and exercised tumor-bearing shark liver oil supplemented (EWSL). Training sessions consisted of 6 bouts, 30 seconds each with 50% body-weight load attached to the trunk followed by 1 minute of resting (jump training). Five minutes after the finish jump training the exercise groups were subjected to 30 minutes of continuous swimming with a load equivalent to 6% of body weight, 4 times a week during 8 weeks. Tumor cells were injected at the 6th training week and all groups we.. Read More»
  DOI: 10.4172/1948-5956.1000254

  Abstract PDF