Molecular Biomarkers & Diagnosis

Fabrizio Zanconati

Publications

• Research Article
  Evaluation of Sentinel Lymph Node Intraoperative Touch Imprint Cytology in Breast Cancer Surgery
  Author(s): Cristiana Iacuzzo, Marina Troian, Laura Bonadio, Deborah Bonazza, Chiara Dobrinja, Gabriele Bellio, Serena Scomersi, Fabiola Giudici, Fabrizio Zanconati and Marina BortulCristiana Iacuzzo, Marina Troian, Laura Bonadio, Deborah Bonazza, Chiara Dobrinja, Gabriele Bellio, Serena Scomersi, Fabiola Giudici, Fabrizio Zanconati and Marina Bortul
  
  Background: One of the strongest prognostic factor for breast cancer is the regional lymph node status, which can be evaluated intraoperatively by sentinel lymph node biopsy. Many methods (e.g. frozen section, touch imprint cytology (TIC) and one-step nucleic-acid amplification) are available to detect metastatic cells in axillary lymph nodes. The aim of this study is to evaluate the feasibility of using TIC to detect metastatic cells in sentinel lymph nodes. Methods: This is a retrospective single center cohort analysis conducted on prospectively recorded data. The study included all patients admitted to the Department of General Surgery of Trieste University Hospital for invasive clinically node-negative breast cancer who underwent sentinel lymph node assessment by means of TIC. Results: Between January 2015 and .. Read More»
  DOI: 10.4172/2155-9929.1000359

  Abstract PDF