Medicinal Chemistry

Fang Jing

Publications

• Research Article
  Dietary Vanadium Induces Decrease in Antioxidant Enzyme Activities and Oxidative Stress in the Spleens of Broilers
  Author(s): Cui Wei, Cui Hengmin, Peng Xi, Fang Jing, Zuo Zhicai, Liu Xiaodong and Wu BangyuanCui Wei, Cui Hengmin, Peng Xi, Fang Jing, Zuo Zhicai, Liu Xiaodong and Wu Bangyuan
  
  The purpose of this 42-day study was to evaluate the risk of oxidative stress in the spleens induced by dietary vanadium through determining changes in antioxidant enzymes and oxidation products. A total of 420 one-day-old avian broilers were divided into six groups. There were 70 broilers in each group. The broilers were fed on a cornsoybean basal diet as a control diet (vanadium 0.073 mg/kg) or the same diet amended to contain 5 mg/kg, 15 mg/kg, 30 mg/kg, 45 mg/kg and 60 mg/kg vanadium supplied as ammonium metavanadate (NH4VO3). When compared with those of the control group, the splenic and serum vanadium contents were increased in the 15 mg/kg, 30 mg/kg, 45 mg/ kg and 60 mg/kg groups. Also, the splenic and serum superoxide dismutase (SOD) activities were greatly depressed in the 45 mg/kg and 60 mg/kg groups; the glutathione peroxidase (GSH-Px) activitie.. Read More»
  DOI: 10.4172/2161-0444.1000110

  Abstract PDF