Laboratory of Human and Experimental Pathology, Pasteur Institute of Tunis, Tunisia, Institut Pasteur de Tunis,
13, Place Pasteur, 1002 Tunis
Tunisia
Research Article
Prognostic Value of Artificial Neural Network in Predicting Bladder Cancer Recurrence after BCG Immunotherapy
Author(s): Faouzia Ajili, Ben Mhamed Issam, Saber Abid, Amine Darouiche, Mohamed Chebil and Samir BoubakerFaouzia Ajili, Ben Mhamed Issam, Saber Abid, Amine Darouiche, Mohamed Chebil and Samir Boubaker
Background: Artificial neural network (ANN) has been used in medicine to predict either the treatment or the investigative outcomes. The aim of this study was to validate the use of ANN models for predicting recurrence in non muscle invasive bladder cancer (NMIBC) treated by Bacillus Calmette Guerin (BCG) immunotherapy.
Materials and Methods: In this study, we developed a Multilayer Percepteron (MLP) based ANN to detect recurrence in NMIBC through the analysis of histopathologic data. The study includes 308 patients (mean age, 63.92 years; range, 31-92 years) who were treated with transurethral resection followed by BCG-immunotherapy. Time follow-up was 30 months.
Results: In the test group, 39 out of 40 cases were correctly classified by the MLP base neural network with an optimum Mse error (0.02634). Only one case was.. Read More»
DOI:
10.4172/2157-7099.1000226
Journal of Cytology & Histology received 2334 citations as per Google Scholar report