Journal of Nephrology & Therapeutics

Faranak Sharifi

Publications

• Research Article
  Effect of Raloxifen on Renal Function in Post-Menopausal Women with Diabetic Nephropathy: a Double Blind Clinical Trial
  Author(s): Faranak Sharifi, Zahra Shajari, Mahnaz Rahimi and Nouraddin MousavinasabFaranak Sharifi, Zahra Shajari, Mahnaz Rahimi and Nouraddin Mousavinasab
  
  Background: This study evaluates the effects of the selective estrogen receptor modulators (SERMs), raloxifen, on renal function in post- menopausal women with type 2 diabetes mellitus. Methods: Thirty-seven post-menopausal women with Type 2 diabetes and diabetic nephropathy included in a 4-month, double-blind, placebo-controlled trial. 18 patients received 60 mg raloxifene per day and 19 patients received placebo. Baseline and end-study body mass index (BMI), blood pressure (BP), fasting plasma glucose (FPG), HbA1C, lipid profiles and serum creatinine (Cr) were measured. Albumin/creatinin ratio (ACR) and GFR were calculated for all the participants. Results: Mean ACR log was decreased significantly in the raloxifene group (2.4 ± 0.63 μg/mg vs. 1.89 ± 0.8 μg/ mg; P=0.009), but slight-non-significant.. Read More»
  DOI: 10.4172/2161-0959.1000135

  Abstract PDF