Journal of Cytology & Histology

Fauziah Othman

Publications

• Research Article
  Effect of Pomegranate on Histopathology of Liver and Kidney on Generated Oxidative Stress Diabetic Induced Rats
  Author(s): Anahita Aboonabi, Asmah Rahmat and Fauziah OthmanAnahita Aboonabi, Asmah Rahmat and Fauziah Othman
  
  Oxidative stress has been recommended as a contributory factor in complication and progression of diabetes. The aim of the study was to evaluate the effects of pomegranate on body weight and histopathology of the steptozotocin–nicotiamide (STZ-NA) generated oxidative stress induced diabetic rats. Thirty-two male Sprague- Dawley rats were randomly divided into non-diabetic, diabetic untreated and diabetic treated with pomegranate and Glibenclamide. Experimental diabetes was induced by a single intraperitoneal (i.p) administration of STZ 60 mg/kg body weight (b.w), 15 minutes after the i.p injection of NA (120 mg/kg b.w). Histopathological analyses were conducted on the liver and kidney tissues. While the body weight significantly decreased in the diabetic control group, however it was a significant increase in the diabetic treated group (P<0.05). Destruction of the liver archi.. Read More»
  DOI: 10.4172/2157-7099.1000294

  Abstract PDF