Nuclear Medicine & Radiation Therapy

Flávia Paiva Proença Lobo Lopes

Publications

• Review Article
  Metastatic Medullary Thyroid Cancers: Challenges in Diagnosis with Nuclear Medicine Techniques and the Role of Radionuclide Therapy
  Author(s): Flávia Paiva Proença Lobo Lopes, Fernanda Vaisman, Cencita H Cordeiro de Noronha Pessoa, Luiz de Souza Machado Neto, Michel Pontes Carneiro, Daniel Bulzico and Rossana CorboFlávia Paiva Proença Lobo Lopes, Fernanda Vaisman, Cencita H Cordeiro de Noronha Pessoa, Luiz de Souza Machado Neto, Michel Pontes Carneiro, Daniel Bulzico and Rossana Corbo
  
  Medullary thyroid cancer is a rare tumor driven from neuroendocrine cells. In the last decade there has been important discoveries regarding its genetics and relationship between genotype and phenotype on familial cases. However remains unknown the best approach for patient with maintained high levels of tumor markers such as calcitonin. Most available imaging techniques are able to accurately find metastatic lesions only in advanced disease. Traditionaly, nuclear medicine images are able to find metastatic suspicious lesions before they reach the size to be considered suspicious in conventional studies such as computed tomography scans or magnetic resonance imaging. However in patients with medullary thyroid cancer the ideal radiopharmaceutical for this purpose is yet to be found. Based on the biology of the tumor, some radiopharmaceuticals have been studied for diagnosis and also fo.. Read More»
  DOI: 10.4172/2155-9619.S8-001

  Abstract PDF