Italy
Review Article
Conservative Management of Placenta Accreta by Systemic Metho-trexate: Report of Two Cases and Review of the Literature
Author(s): Marialuisa Framarino-dei-Malatesta, Renzo D’Amelio, Maria Grazia Piccioni, Angela Martoccia, Assunta Casorelli and Francesco PecoriniMarialuisa Framarino-dei-Malatesta, Renzo D’Amelio, Maria Grazia Piccioni, Angela Martoccia, Assunta Casorelli and Francesco Pecorini
Objective: Owing to the growing number of cesarean deliveries, the abnormally invasive placenta-tion so called placenta accreta rate is increasing. Placenta accreta is difficult to manage and traditionally resolved by cesarean hysterectomy after the birth due to the following massive hemorrhage. In recent years different conservative treatments leaving partially or totally the placenta in the uterine cavity have been reported in patients willing to preserve their fertility. Methods: We reviewed literature data about conservative management of placenta accreta in the PubMed, Researchgate and Medline from 2007 to date. We included in the review the studies about the use of methotrexate (MTX) for conservative treatment of placenta accreta. Results: We reported 2 literature reviews and 4 studies about the use of MTX in the management of placenta accreta and 2 unpublished cases treated in .. Read More»
DOI:
10.4172/2165-7920.1000706
Journal of Clinical Case Reports received 1295 citations as per Google Scholar report