Journal of Sports Medicine & Doping Studies

Frank NM Twisk

Publications

• Review Article
  Objective Evidence of Post-exertional “Malaise” in Myalgic Encephalomyelitis and Chronic Fatigue Syndrome
  Author(s): Frank NM TwiskFrank NM Twisk
  
  Essential elements of Myalgic Encephalomyelitis (ME) are muscle (weakness) and tenderness, cognitive deficits, neurological impairments, especially of cognitive, autonomic and sensory functions, but above all, post-exertional“malaise”: a prolonged increase of symptoms after a minor physical and mental exertion. Chronic fatigue Syndrome (CFS) is defined as clinically evaluated, unexplained (persistent or relapsing) chronic fatigue, accompanied by at least four out of eight specific symptoms, e.g., sore throat, unrefreshing sleep, and headaches. Since cognitive deficits and post-exertional “malaise” are not mandatory for the diagnosis CFS, only part of the CFS patient group meets the diagnostic criteria for ME. So, post-exertional “malaise” is considered to be the distinctive feature of ME. However, “.. Read More»
  DOI: 10.4172/2161-0673.1000159

  Abstract PDF