Cancer Science & Therapy

Fritz A. Lerma

Publications

• Research Article
  Relation Between Tumor Size and Range of Motion in IMRT Treatment Planning for Thoracic Lesions
  Author(s): Ivaylo B. Mihaylov, Fritz A. Lerma and Eduardo G. MorosIvaylo B. Mihaylov, Fritz A. Lerma and Eduardo G. Moros
  
  Purpose: To evaluate the relation between tumor size/volume, tumor range of motion, and healthy lung volume in light of radiotherapy motion management paradigm. Materials and Methods: Four patient data sets were considered in this investigation. Each patient underwent time resolved (4D) CT data scan. Mid-ventilation CT data sets, with nominal lung volumes ranging from ~3000 cm3 to ~6000 cm3, were considered for treatment planning. Spheres with pre-specified radii were auto-contoured in the left lower lobes as simulated planning target volumes (PTVs) for each patient. Motion in superior-inferior direction was superimposed on the simulated spherical PTVs, such that motion-inclusive ITVs were generated. Nine-field IMRT treatment plans were created for all lung volumes, different combinations of simulated PTV spherical size and ranges of motion. Three dose levels of 60 Gy, 70 Gy, and 8.. Read More»
  DOI: 10.4172/1948-5956.1000031

  Abstract PDF