Journal of Cytology & Histology

Fumihiko Ookubo

Publications

• Case Report
  Characteristic Cytological Features of Cervical Clear Cell Adenocarcinoma: A Report of 4 Cases
  Author(s): Kenzo Sonoda, Miwako Nogami, Masaki Naka, Fumihiko Ookubo, Hiroaki Kobayashi, Hideaki Yahata, Kaoru Okugawa, Eisuke Kaneki, Yoshinao Oda and Kiyoko KatoKenzo Sonoda, Miwako Nogami, Masaki Naka, Fumihiko Ookubo, Hiroaki Kobayashi, Hideaki Yahata, Kaoru Okugawa, Eisuke Kaneki, Yoshinao Oda and Kiyoko Kato
  
  We experienced 5 cases of clear cell adenocarcinoma (CCAC) of the cervix in the 10-year period from 2003 to 2012. Because a specimen from one of the cases was poorly preserved, we analyzed cytological features of the 4 remaining cases. Characteristic large, pale-staining atypical cells with prominent, round nuclei were seen in all cases. Additionally, a hobnail appearance and basement membrane-like substance were detected in 3 cases, and a mirror ball cluster-like morphology was found in 1 case. Cervical CCAC has been reported to be difficult to diagnose by cytology; however, we were able to diagnose these 4 cases by recognizing several characteristic cytological features... Read More»
  DOI: 10.4172/2157-7099.1000196

  Abstract PDF