Cardiovascular Diseases & Diagnosis

Gary Adams

Publications

• Review Article
  Statins as a Primary Prevention: Which One is Most Effective? A Systematic Review and Meta-Analysis
  Author(s): Gemma Figg, Alex Jervis, Susannah Champion, Jane Langley and Gary AdamsGemma Figg, Alex Jervis, Susannah Champion, Jane Langley and Gary Adams
  
  Background: Type 2 diabetics are at high risk of atherosclerosis and Cardiovascular (CV) events due to their associated dyslipidemic profile. Adverse levels of the lipid triad: Low-Density Lipoprotein Cholesterol (LDL-C), High- Density Lipoprotein Cholesterol (HDL-C) and Triglycerides (TGs), have been shown to be major contributing factors. Statins (HMG-CoA reductase inhibitors) are recommended as first-line lipid therapy as evidence has shown their effectiveness in primary and secondary prevention of CV events. However, there is limited evidence specifically focused on primary prevention in Type 2 Diabetes Mellitus (T2DM) and dyslipidemia. The main purpose of this review was to assess the efficacy of statins in type 2 diabetics with dyslipidemia for the primary prevention of CV events. Methods: A systematic review was carried out to determi.. Read More»
  DOI: 10.4172/2329-9517.1000109

  Abstract PDF