Journal of Surgery

Gaurav Agarwal

Publications

• Research Article
  High Resolution Magic Angle Proton Magnetic Resonance Spectroscopy (HRMAS) in Intact Sentinel Node Biopsy from Breast Cancer Patients: A New Diagnostic Tool!
  Author(s): Surender Kumar, Shailendra Kumar, Raja Roy, Ankita Singh Rathore, Madhu Mati Goel, Gaurav Agarwal and Sandeep KumarSurender Kumar, Shailendra Kumar, Raja Roy, Ankita Singh Rathore, Madhu Mati Goel, Gaurav Agarwal and Sandeep Kumar
  
  Introduction: The extent of axillary lymph node involvement is one of the most important prognostic markers in patients of breast cancer. However, axillary dissection is associated with significant morbidity. The intra-operative sentinel node biopsy (SNB) provides a basis for omitting the routine axillary clearance however; use of in-house frozen section histopathology is required in order to substitute later. We report the use of in vitro high resolution magic angle proton magnetic resonance spectroscopy (HRMAS) for assessing the axillary nodal status with increased sensitivity. Methods: Freshly removed axillary lymph nodes (n=17) obtained during sentinel node biopsy from 17 different patients were bisected. One segment of the bisected node was snap frozen and transported to HRMAS labo.. Read More»
  DOI: 10.7438/1584-9341-11-2-2

  Abstract PDF